Poisonous Frogs & Toads You Should Know About 1. Pickerel Frog Releases skin secretions toxic to predators. 2. Green-and-Black Poison Dart Frog Famous for its powerful skin toxins used by Indigenous hunters. 3. American Toad Secretes bufotoxins that can irritate eyes, skin, and mouths of predators. 4. Colorado River Toad Sonoran Desert Toad Produces powerful toxins; highly dangerous if ingested. 5. Western Toad Emits mild toxins as a defense against predators. 6. Fowlers Toad Produces skin secretions that can be irritating to humans and animals. 7. Cane Toad One of the most toxic toads in the world; its poison can kill pets and wildlife. 8. Oak Toad Small but secretes toxins that can deter predators. Safety Tips When Around Frogs & Toads Do not touch wild frogs or toads with bare hands. Keep pets away from themespecially dogs. Wash hands thoroughly if contact occurs. Never attempt to eat or handle these species. Frogs and toads are fascinating and vital to ecosystems, but some come with serious risks. Admire them from a safe distance to protect both yourself and the animal!